I have a first version of Smallapack ported on Squeak yet, but that has not been that easy!
Still, the Smallapack port is bleding edge and not really functional.
Here is my little story.

Problems encountered porting Smallapack on Squeak:

first problem: (minor) line end conventions in file.

I develop under linux where line end convention is LF.
I found Squeak very tyrannic with its Mac CR convention...
All my attempts to work around failed and i had to resolve myself converting my files to CR before going to Squeak...

second problem: lack of FFI examples

How to pass an array of structures? (the Complex Matrix case)
How to load a library before another? (mostly in Unix environment)
How to define a specific library path?

All these questions were resolved slowly...

I proposed a new feature to automagically free allocated memory at http://bugs.squeak.org/view.php?id=3692
I did not invent much, this kind of utility exists in VW for a long time.

I also experimented an infinite loop as described at http://bugs.squeak.org/view.php?id=3691

third problem: method can only have 15 arguments

LAPACK have some functions with more than 15...
I circumvent this problem using a trick: pass a single array of arguments.
I implemented Compiler tweak for having this automated (and not crafted by hand...)
This can be found at http://bugs.squeak.org/view.php?id=2918

fourth problem: a strange bug in unix FFI

This bug is described at http://bugs.squeak.org/view.php?id=3929
Yet, i am stuck by this one...
It prevents my SUnit TestCase to work.

fiveth problem: understand Squeak tools Monticello, SqueakMap, ...

Not really a problem, i find Monticello is great.
But as a Newbie, there's always a learning curve...

sixth problem: no Callback framework

I need such framework for example in Schur algorithm
(a function for sorting eigenvalues is necessary)

seventh problem: bugs in Number library

especially, with floating point arithmetic...
To be fair, most of these bugs are found in major Smalltalk implementations
(VW, Squeak, Dolphin, ST/X, gst, ...)
But Squeak had a little bit more bugs than others...
You can see my patches at:
 http://bugs.squeak.org/view.php?id=3564 , 3568 , 3512 ,  3360 ,  3504 , 3493 , 3374 , 3373 , 2688 , 3133


What i like in Squeak:

FFI is somehow more simple than VW DLLCC.
The ability to work in Smalltalk memory with ByteArray is also simpler than allocating/freeing external heap.
Squeak community is great.
Monticello
Mantis bug database

All in all, porting to Squeak was a very interesting experience!